Shoc2 gene
Web16 Sep 2024 · SHOC2 is a scaffold protein that acts as part of the RAS-SHOC2-PP1 phosphatase complex to facilitate interactions of core signaling partners of the ERK pathway 1.Since ERK1/2 signaling is involved ... WebExpression of SHOC2 in cancer - Summary - The Human Protein Atlas SHOC2 PATHOLOGY CANCER ANTIBODIES AND VALIDATION Dictionary Human pathology PROGNOSTIC SUMMARYi Gene product is not prognostic Show all RNA EXPRESSION OVERVIEWi TCGA dataseti RNA cancer category: Low cancer specificity
Shoc2 gene
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WebSoc-2 suppressor of clear homolog (SHOC2) is a gene that encodes a protein that functions in the RAS/ERK MAP kinase signaling pathway as a scaffold linking Ras to downstream … WebFull gene name according to HGNC. SHOC2 leucine rich repeat scaffold protein. Gene namei. Official gene symbol, which is typically a short form of the gene name, according …
Web5 Mar 2024 · genes in panel. prev next actb 2 actg1 1 alpl 4 alx4 4 arsb 2 asxl1 5 b3gat3 4 braf 2 cdc45 5 chd7 2 colec11 3 ctsk 3 cyp26b1 3 efnb1 4 erf 4 fam20c 3 fgfr1 4 fgfr2 4 fgfr3 4 flna 4 gli3 3 gnas 4 gnptab 4 hnrnpk 3 huwe1 3 ids 4 idua 4 ift122 4 ihh 4 il11ra 4 jag1 3 kat6a 4 kmt2d 3 kras 3 ltbp1 3 megf8 3 msx2 4 nfia 4 p4hb 2 phex 4 por 4 ptch1 3 …
WebThe scaffold protein Shoc2 is a critical modulator of ERK1/2 signals, and mutations in the shoc2 gene lead to the human developmental disease known as Noonan-like syndrome with loose anagen hair ... Web1 Jun 2024 · The SHOC2 gene affects proliferation, survival, and differentiation of epithelial stem cell-derived cells in hair follicles; however, the relationship between SHOC2 mutations and the other cutaneous pathologies seen specifically in NS/LAH remains unclear. 7.
Web17 Jun 2008 · Waterfall plot of ratio of log (base 2) post- versus preintervention of SHOC2 gene expression comparing microarray (filled bars) to the mean of three independent replicate QRT-PCR (cross-hatched bars) measurements. No QRT-PCR data are shown for 14 of the 30 patients for whom insufficient needle biopsy RNA was available, precluding …
WebThe recently identified SHOC2 mutation (p.Ser2Gly) causes Noonan syndrome with loose anagen hair. We report five patients with this mutation. All had skin hyperpigmentation, … cherish \u0026 share馬口鐵磁鐵WebSoc-2 suppressor of clear homolog (SHOC2) is a gene that encodes a protein that functions in the RAS/ERK MAP kinase signaling pathway as a scaffold linking Ras to downstream signal transducers. flights from joplin mo to birmingham alWebData suggest that Shoc2 regulates the spatio-temporal patterns of the Ras-ERK signaling pathway primarily by accelerating the Ras-Raf interaction. no evidence of leukemogenic … cherish u congletonWebName Identifier Synonyms; Noonan syndrome : DOID:3490 Turner's phenotype, karyotype normal (disorder) chronic myeloid leukemia cherish \u0026 natural shopWebSHOC2 Leucine Rich Repeat Scaffold Protein Gene Mutation; Soc-2 Suppressor of Clear Homolog Gene Mutation; SOC2 Gene Mutation; SUR8 Gene Mutation Definition A change … flights from joplin mo to dallas txWebSHOC2. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Official gene symbol, which is typically a short form of the gene name, according to HGNC. Full gene name according to HGNC. cherish uk leighWebA key phosphatase that mediates this dephosphorylation step is a heterotrimeric complex composed of MRAS, SHOC2, and protein phosphatase 1 (PP1) ().SHOC2 is a ubiquitously expressed protein composed almost exclusively of leucine-rich repeats (LRRs) that was originally identified in Caenorhabditis elegans as a positive modulator of the ERK pathway … flights from jonesboro ar