WebFeb 2, 2024 · Our analytical framework, dynamo, consists of four integral stages: 1) estimation of genome-wide kinetic rate constants and velocity vectors, 2) reconstruction of single-cell vector field functions with the resultant cell state and velocity samples, 3) in-depth analyses leveraging various differential geometry analyses, and 4) predictions of ... WebDynamo. : Mapping Vector Field of Single Cells. Single-cell (sc)RNA-seq, together with RNA velocity and metabolic labeling, reveals cellular states and transitions at unprecedented resolution. Fully exploiting these …

dynamo-release/README.md at master - Github

WebSingle-cell RNA-seq pseudotime estimation algorithms. Single cells, many algorithms. The goal of this page is to catalog the many algorithms that estimate pseudotimes for cells based on their gene expression levels. This problem is also referred to as single-cell trajectory inference or ordering. Web•Vector fields reveal the timing and mechanisms of human hematopoiesis •Dynamo allows cell-state transition path and in silico perturbation predictions . Summary. Single-cell (sc)RNA-seq, together with RNA velocity and metabolic labeling, reveals cellular states and transitions at unprecedented resolution. teacher wage calculator

Mapping transcriptomic vector fields of single cells

WebQiu X, Zhang Y, Yang D, et al. Mapping vector field of single cells[J]. Biorxiv, 2024. 这个 RNA velocity and beyond 系列之后大概会写 Theory 部分 ，主要介绍 model detail，怎么 estimate parameter等，最后写 beyond 的部分，也就是dynamo 的内容。 欢迎大家在评论区讨论（虽然我估计没什么人看hhhh） WebDynamo: Mapping Transcriptomic Vector Fields of Single Cells. Inclusive model of expression dynamics with metabolic labeling based scRNA-seq / multiomics, vector … WebFeb 17, 2024 · In this work, we introduced dynamical systems theory and differential geometry analyses to single-cell genomics. A dynamical system describes the time … teacher wacky wednesday