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Atf6a kda

WebFeb 21, 2024 · Lastly, ATF6a is an ER transmembrane protein. Upon accumulation of misfolded proteins in the ER, ATF6a is released from GRP78 and translocates to the Golgi apparatus, where it is cleaved sequentially by site-1- and site-2-proteases. WebATF6, ATF6 alpha, ATF6A Observed MW 50 kDa,100 kDa. Application. Tested Application ELISA, WB Recommended dilution WB: 1:200-1:2000. Uniprot information. UniProt ID P18850. Images. Image 4. MCF-7 cells were subjected to SDS PAGE followed by western blot with FNab10404(ATF6 Antibody) at dilution of 1:1000.

Nonstructural proteins 2C and 3D are involved in autophagy as …

WebSep 1, 2014 · ATF6a is cleaved by trans-membrane proteases and translocated to the nucleus, where it activates the genes responsible for the ER stress response [ 36, 37 ]. ATF6a cleavage was analysed in BHK-21 cells to assess whether EMCV infection or the expression of EMCV 2C or 3D protein activate the ATF6a pathway. WebPolyclonal Antibodies Monoclonal Antibodies Recombinant Antibodies Back Secondary Antibodies Anti-Rabbit Anti-Mouse Anti-Hamster Anti-Rat Anti-Goat Anti-Sheep Anti-Chicken Anti-Human EasyBlot Antibodies (for IP/WB) Back Antibody Panels Primary Antibody Panels Secondary Antibody Panels Back ELISA Antibody Pairs & Kits ELISA Kits ELISA … gamazine houses images https://pozd.net

Anti-ATF6 antibody [C3], C-term (GTX104820) GeneTex

Webtranscription factors, the most studied of which is ATF6a. When released from GRP78, ATF6a, a single-pass ER trans-membrane protein, translocates to the Golgi where a cleavage event releases a cytoplasmic domain which is a potent but short-lived transcription factor (6). ATF6a, similar to XBP1, WebJun 1, 2015 · ATF6 is a member of the ATF/CREB (cAMP response element–binding protein) family of basic leucine-zipper (bZIP) transcription factors encoded by two paralogs, ATF6 and ATF6B. ATF6A is a key... WebJun 17, 2024 · ATF6α in unstressed cells exists as a mixture of disulfide-linked oligomers and monomers. Upon stress, the interchain and intrachain disulfides are reduced giving rise to the suggestion that only the reduced monomeric form … black crowes house of blues las vegas

Coordinated signaling of activating transcription factor 6α and ...

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Atf6a kda

ATF6 Monoclonal Antibody (8D3) (MA5-34918) - Thermo Fisher …

WebSection I - Importation Information (Use a separate ATF Form 6A (5330.3C) to describe articles imported under each permit.Also, use a separate form for each shipment under … WebDec 10, 2016 · The 29 kDa CHOP is a member of the C/EBP family of transcription factors. CHOP was upregulated in VZV-infected monolayers incubated for 48 h, in concert with the appearance of the spliced form of XBP1 . The parallel results for XBP1 and CHOP suggested that ER stress conditions became extreme as most of the cells became infected.

Atf6a kda

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WebATF6a (90 kDa), which, like XBP1, is a basic leucine zipper transcription factor.11 ATF6a is expressed constitutively in an inactive form. ER stress leads to dissociation of ATF6a from BiP resulting in the translocation of ATF6a to the Golgi apparatus. The subsequent proteolytic cleavage of its cytosolic bZIP domain allows for the release of ... WebATF6 is originally a 90 kDa type II transmembrane glycoprotein that is converted to a 50 kDa soluble nuclear form, retaining its N-terminal domain, including the leucine zipper. …

WebAfter 30 min of TG treatment, a V5 reactive band was detected migrating at about 90 kDa (Fig. 3A). When cells were pretreated with ammonium chloride, before treatment with … WebThis form is used to obtain a release from the U.S. Customs and Border Protection (CBP) and notify ATF of actual importation of defense articles imported pursuant to an approved …

WebPage 5 TH-F6A/F7E CIRCUIT DESCRIPTION The first amplifier is divided into four bands: 100 kHz - 50 signal demodulated by the diode detection circuit is output. MHz, 50MHz - … WebMay 25, 2024 · Indeed, ATF6α is a potent transcriptional activator whereas ATF6β, a poor transcriptional activator, may inhibit activation by ATF6α [ 7 ]. In contrast with the protein kinases PERK and IRE1 (type I transmembrane proteins), ATF6α is a 90 kDa type II transmembrane glycoprotein and member of the bZIP transcription factor family [ 8 ].

WebFeb 15, 2016 · ATF6a, Chondrocyte hypertrophy, UPR, Transcription factor, Regulation INTRODUCTION In eukaryotic cells, endoplasmic reticulum (ER) stress is known to initiate a signaling pathway called the unfolded protein response (UPR) ( Hetz, 2012; Zhang and Kaufman, 2004; Ron and Walter, 2007 ).

WebAntibodies (Ab) against BIP (78 kDa), ATF6 (90 kDa), glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and horseradish peroxidase (HRP)-conjugated goat anti-rabbit secondary Ab were purchased from Proteintech, Wuhan, China. Phosphorylated PERK (p-PERK; Thr 981, 125 kDa) Ab was purchased from Santa Cruz Biotechnology, Santa … gamazine wall fenceWebJun 17, 2024 · ATF6α is normally resident within the ER; however, after ER stress, it traffics to the Golgi apparatus. Here, it is cleaved sequentially by site-1 protease (S1P) and site … black crowes huntsvilleWebMar 21, 2024 · GeneCards Summary for ATF6 Gene. ATF6 (Activating Transcription Factor 6) is a Protein Coding gene. Diseases associated with ATF6 include Achromatopsia 7 … HMOX1 (Heme Oxygenase 1) is a Protein Coding gene. Diseases associated with … XBP1 (X-Box Binding Protein 1) is a Protein Coding gene. Diseases associated with … SERPINE1 (Serpin Family E Member 1) is a Protein Coding gene. Diseases … FCGR3A (Fc Gamma Receptor IIIa) is a Protein Coding gene. Diseases … EPCAM (Epithelial Cell Adhesion Molecule) is a Protein Coding gene. Diseases … MPZ (Myelin Protein Zero) is a Protein Coding gene. Diseases associated with … SMARCA4 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator … HEXA (Hexosaminidase Subunit Alpha) is a Protein Coding gene. Diseases … IGFBP7 (Insulin Like Growth Factor Binding Protein 7) is a Protein Coding gene. … EGR1 (Early Growth Response 1) is a Protein Coding gene. Diseases … black crowes imagesWebunfolded protein response, activated by oasis family transcription factors, promotes astrocyte differentiation gamazine paint south africaWeb75 kDa. ( Note) Product Note The immunogen sequence of this antibody is within the cleaved form of ATF6 alpha. Predict Reactivity ... ATF6A Background This gene encodes a transcription factor that activates target genes for the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Although it is a transcription factor, this ... gamazine wall and decorWebMay 1, 2024 · Furthermore, ATF6α inhibition through Ceapin-A7, or Atf6a deletion, disrupted transforming growth factor β (TGFβ)-mediated activation of primary human hepatic stellate cells (hHSCs) or murine hepatic stellate cells (mHSCs), respectively. We investigated the fibrogenic role of ATF6α in vivo through conditional HSC-specific Atf6a deletion. gamazine prices around gautengWeb75 kDa. ( Note) Product Note This antibody was raised against the C-terminus of human ATF6 alpha, meaning it can only detect the uncleaved form. ... ATF6A Cellular … gamazine powder for plants